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16-Dehydroprogesterone

Payment
T/T, west union, money gram,paypal
Delivery
within 3-5 working days
Origin
China
Packaging
1kg/bag or as required
Inspection
HPLC,UV
Samples
Free
COA
sales@nitobioc.com
Purity
99%
Standard
In house
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Product Feature
Product name: 16-dehydroprogesterone
CAS No: 1096-38-4
Molecular Weight: 312.45
Molecular Formula: C21H28O2

Product Specification / Models
Purity: 98%min
Appearance:white powder.
Packing: 1kg/bag or as required.
Storage: Store in cool and dry area and keep away from direct sunlight.
Shelf life: 2 years, if keep in formal storage condition.

Application
16-Dehydroprogesterone reductase (16-DHPR) activity was present in cell extracts of Eubacterium sp. strain 144 only when the organism was grown in the presence of steroids containing a delta 16-17 double bond and C-20-ketone. Cells grown with 16-dehydropregnenolone contained 16-DHPR activity but lacked delta 4-5-3-keto steroid reductase activity. Pyruvate or sodium dithionite served as electron donors for 16-DHPR and both reactions required methyl viologen as an electron carrier. Neither NADH nor NADPH, with or without flavin nucleotides, were used by 16-DHPR. Enzyme activity was detected in the cytoplasmic fraction (40%) and membrane fraction (20%) of crude cell extracts, but 40% of the activity was unaccounted for following ultracentrifugation. 16-DHPR activity was unaffected by pH in potassium phosphate buffer over the range 5.0 to 8.5, but was inhibited by Tris-HCl above pH 7.0. 16-DHPR activity was inhibited by sulfhydryl reagents, but inhibitors of electron transport reactions or metal chelators did not affect the enzyme.

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