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DHEA Sulphate Sodium
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- 1kg/bag or as required
DHEAS/DHEA Sulphate/Sodium dehydroepiandrosterone sulfate
Dehydroepiandrosterone sulfate (DHEAS) is a metabolite of dehydroepiandrosterone that is the major secretory product of adrenal glands and is the predominant circulating precursor for active steroid hormones in humans.For example, in the fetoplacental-maternal unit, DHEAS acts as the primary precursor for placental estrogen biosynthesis.A normal circulating concentration of DHEAS is ~10µM in young adults and is dramatically increased in some adrenocortical disorders.
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Product Name: DHEAS/DHEA Sulphate
Alias: Sodium dehydroepiandrosterone sulfate
CAS No: 1099-87-2
Einecs No: 214-152-2
Product Specification / Models
Appearance: close to white powder.
Packing: 1kg/bag or as required.
Storage: Store in cool and dry area and keep away from direct sunlight.
Shelf life: 2 years, if keep in formal storage condition.
Dehydroepiandrosterone (DHEA) and its sulfate ester, DHEAS, together represent the most abundant steroid hormones in the human body. Nonetheless, their physiological significance, their mechanisms of action and their possible roles in human disease are not well understood. Highlighting the potential health significance of DHEA and DHEAS, concentrations of these hormones in humans typically decrease steadily with age, approaching a nadir at about the time many diseases of aging become markedly more prevalent. Observations such as these, coupled with basic and preclinical demonstrations of DHEA's biological effects, fostered hope that restoring DHEA to youthful levels might, conservatively, increase well-being and, optimistically, extend life, protect the brain, and retard the ravages of aging. Almost from the time of their initial discovery and synthesis, DHEA and DHEAS were evaluated in the treatment of neuropsychiatric disorders, with published reports appearing as early as 1952 [272; 298]. Large-scale enthusiasm for DHEA as a potential neuropsychiatric therapy languished until the late 1980s through the mid-1990s, when an expanding body of preclinical data plus the first adequately controlled clinical trial  renewed hopes for therapeutic potential.
The field of inquiry into the neurobiological actions of DHEA and DHEAS (jointly referred in this article as "DHEA(S)") is rapidly growing. The goal of the present article is to review the basic and preclinical studies of DHEA(S)' biological actions in the brain and their purported mechanisms of action,differences in endogenous circulating concentrations in normal individuals and patients with certain neuropsychiatric illnesses (depression, anxiety, schizophrenia and dementia), and the therapeutic potential of DHEA(S) in treating these neuropsychiatric conditions.
DHEA Sulphate Sodium 1099-87-2
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DHEA (Dehydroepiandrosterone, Prasterone) 53-43-0