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Estrone

Payment
T/T, West Union,money gram,paypal
Delivery
within 3-5 working days
Origin
China
Packaging
1kg/bag or as required
Inspection
HPLC,UV
Samples
Free
COA
sales@nitobioc.com
Purity
99%
Standard
USP,BP

Product Description
Estrone is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

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Product Feature
Estrone
Alias: 3-hydroxyestra-1,3,5(10)-triene-17-one
CAS No:53-16-7
MF:C18H22O2
MW:270.37
EIN:200-164-5
 
Product Specification / Models
Purity: 98%
Appearance: close to white powder.
Packing: 1kg/bag or as required.
Storage: Store in cool and dry area and keep away from direct sunlight.
Shelf life: 2 years, if keep in formal storage condition.
 
Application
Therapeutic Estrone is the synthetic form of a naturally occurring estrogen estrone. Estrone diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated hormone-receptor complex gets translocated to the nucleus where it binds to the estrogen response element on the DNA and promotes the transcription of target genes involved in the functioning of the female reproductive system and secondary sex characteristics. Estrone increases the hepatic synthesis of sex hormone binding globulin (SHBG), thyroid-binding globulin (TBG), and other serum proteins, as well as suppresses the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.

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